The eminent neurologist examines the stories of people whose symptoms are so strange that even their doctor struggles to know how to treat them. A man who sees cartoon characters running across the room; a teenager who one day arrives home with inexplicably torn clothes; a girl whose world turns all Alice in Wonderland; another who transforms into a ragdoll whenever she even thinks about moving. The brain is the most complex structure in the universe and neurologists must puzzle out life-changing diagnoses from the tiniest of clues – it’s the ultimate in medical detective work. O’Sullivan’s book about psychosomatic illness, It’s All in Your Head, won both the Wellcome Book Prize and the Royal Society of Biology Book Prize. She talks to Rosie Boycott.